The Science Behind MX3

The Science of MX3

The MX3 Hydration Testing System is the world’s first point-of-care diagnostic platform that uses saliva to measure important health markers in real-time. By unlocking the potential of saliva for personal testing, MX3 users can conveniently measure and track aspects of their own physiology anytime without visiting a doctor or waiting for a lab to provide results.

Key to the system is the world’s first electrochemical test strip for salivary osmolarity (SOSM) testing. SOSM has been proven to be a sensitive and reliable marker of hydration status. Measurements with the MX3 Hydration test strip can reliably characterize hydration status in seconds—anytime and anywhere.

MX3 performs the same osmolarity test as a much larger, heavier, and more expensive laboratory osmometer. MX3 truly puts the power of a lab in the palm of your hand.

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Transforming Testing with Saliva

Over the last 20 years, researchers have identified saliva as a rich source of biomarkers that can be used to monitor health and wellness, including hormones, metabolites, nucleic acids and more. Collection of saliva is safer and less invasive than blood or urine, making it an excellent candidate for field testing of health status without the need for trained medical staff.

Saliva analysis is not without challenges. Unlike blood, which is tightly regulated by the body, saliva can vary greatly in volume, viscosity, consistency and acidity. Additionally, the concentration of most analytes is much lower in saliva than other bodily fluids, mandating high sensitivity-detection techniques. Because of these challenges, very few saliva tests have made their way out of the laboratory. Until now.

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MX3’s Innovation

MX3 has spent years developing a system that makes measurement of raw saliva fast and reliable. Key breakthroughs in a technology sequence of microfluidics, electrochemistry, signal processing and machine learning address the unique complexities of saliva.

The result is a world-first electrochemical saliva analysis system that provides personalized, laboratory-grade, actionable information in the palm of your hand.

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The Critical Importance of Hydration

Hydration impacts every physiological system in the body. Proper hydration is essential for optimal physical and mental performance. Despite its importance, hydration is very difficult to assess reliably and conveniently.

MX3 started its hydration development by focusing on salivary osmolarity (SOSM) as a proven marker of status. Multiple studies support SOSM, including its advantages over urine tests and other common assessment techniques for determining acute dehydration. We are innovating further today to enhance our perspectives on hydration and other critical health markers.

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